{"id":1352,"date":"2018-02-09T11:20:00","date_gmt":"2018-02-09T11:20:00","guid":{"rendered":"https:\/\/www.groupactionlawyers.co.uk\/blog\/?p=1352"},"modified":"2018-02-09T11:20:00","modified_gmt":"2018-02-09T11:20:00","slug":"hospitals-doctors-warned-over-using-intercept-liver-disease-drug","status":"publish","type":"post","link":"https:\/\/www.groupactionlawyers.co.uk\/blog\/hospitals-doctors-warned-over-using-intercept-liver-disease-drug","title":{"rendered":"Hospitals and Doctors warned over using Intercept Pharmaceuticals liver disease drug"},"content":{"rendered":"

Regulators have issued Doctors and Hospitals with a warning over Intercept Pharmaceuticals liver disease drug after 19 people have reportedly died after taking too much of it.<\/p>\n

Regulators also noted 11 cases of serious liver injury after taking the drug as well.<\/p>\n

The warning prompted the company’s shares to reportedly plummet down by 24.9%, to $73.70. The drop is thought to be the company’s biggest loss since November 2014, Bloomberg reports.
\n
\nThe regulator warning said that the drug, “is being incorrectly dosed in some patients with moderate to severe decreases in liver function resulting in an increased risk of serious liver injury and death”.<\/p>\n

It has also been reported that some patients with mild liver disease who are receiving the correct dose also suffered liver injury, indicating that the problem could lie with the medication itself<\/strong>, rather than just an overdose.<\/p>\n

The liver is a vital organ that primarily filters toxins from the blood before it makes its way to the rest of the body. It detoxifies chemicals and metabolises drugs, helping to keep our body’s toxin free.<\/p>\n

Those suffering with liver disease and reduced liver function may not be able to do this as effectively. This kind of drug is, therefore, very important to those with liver problems<\/strong>.<\/p>\n

Ocaliva is used to treat a rare liver disease called Primary Biliary Cholangitis (PBC). This condition can inflame, damage and destroy bile ducts, which can lead to a build-up of bile that can block up the liver. This can stop the liver from working effectively in filtering out toxins in our blood. Ocaliva works by reducing alkaline phosphatase linked to PCB, and the drug was notably only approved last year.<\/p>\n

At the moment, Ocaliva does not list death as one of its risks. We wonder whether Intercept will need to recall the drug to adjust its formula, or at least to relabel it to include the fatal risk, and perhaps consider whether the drug is more dangerous than anticipated.<\/p>\n

The Medicines and Healthcare products Regulatory Agency (MHRA) has yet to make any statement over Ocaliva, which is distributed in the U.K. The drug received approval from the National Institute for Health and Care Excellence (NICE) for routine use by our NHS in March 2017. Intercept’s President, Lisa Bright, reportedly praised NICE’s “very rapid decision” to approve the drug.<\/p>\n

According to Symphony Health Solutions, around 15,000 prescriptions for Ocaliva have been made since it was approved and hit the market.<\/p>\n","protected":false},"excerpt":{"rendered":"

Regulators have issued Doctors and Hospitals with a warning over Intercept Pharmaceuticals liver disease drug after 19 people have reportedly died after taking too much of it. Regulators also noted 11 cases of serious liver injury after taking the drug as well. The warning prompted the company’s shares to reportedly plummet down by 24.9%, to … Continue reading Hospitals and Doctors warned over using Intercept Pharmaceuticals liver disease drug<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":1359,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[5],"tags":[24],"class_list":["post-1352","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medical","tag-prescription-drugs"],"yoast_head":"\nHospitals And Doctors Warned Over Using Intercept Liver Disease Drug<\/title>\n<meta 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The impact for the victims in these kinds of cases can, of course, be severe; especially if the drugs being recalled are for\u2026","rel":"","context":"In "Group Actions"","block_context":{"text":"Group Actions","link":"https:\/\/www.groupactionlawyers.co.uk\/blog\/category\/group-actions"},"img":{"alt_text":"liver disease drug warning","src":"https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/liver-disease-drug-warning-min.png?fit=725%2C250&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/liver-disease-drug-warning-min.png?fit=725%2C250&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/liver-disease-drug-warning-min.png?fit=725%2C250&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/liver-disease-drug-warning-min.png?fit=725%2C250&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":1404,"url":"https:\/\/www.groupactionlawyers.co.uk\/blog\/birth-defects-reportedly-caused-utero-exposure-epilepsy-drug","url_meta":{"origin":1352,"position":3},"title":"Birth defects reportedly caused by in-utero exposure to Epilepsy Drug","author":"Admin","date":"28th February 2018","format":false,"excerpt":"A drug that helps control epileptic seizures has been reportedly linked to birth defects and should not be used by pregnant women or women of child-bearing potential. Depakote was created by French pharmaceutical drug company Sanofi back in 1967. The British equivalent, Epilim, has been available since 1973. The drug\u2026","rel":"","context":"In "Medical"","block_context":{"text":"Medical","link":"https:\/\/www.groupactionlawyers.co.uk\/blog\/category\/medical"},"img":{"alt_text":"pregnancy epilepsy drug concerns","src":"https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/pregnancy-epilepsy-drug-concerns.png?fit=1200%2C414&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/pregnancy-epilepsy-drug-concerns.png?fit=1200%2C414&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/pregnancy-epilepsy-drug-concerns.png?fit=1200%2C414&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/pregnancy-epilepsy-drug-concerns.png?fit=1200%2C414&ssl=1&resize=700%2C400 2x, https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/pregnancy-epilepsy-drug-concerns.png?fit=1200%2C414&ssl=1&resize=1050%2C600 3x"},"classes":[]},{"id":1189,"url":"https:\/\/www.groupactionlawyers.co.uk\/blog\/regulatory-advice-kratom-drug-after-36-deaths","url_meta":{"origin":1352,"position":4},"title":"Regulatory advice on Kratom drug after 36 deaths","author":"Admin","date":"22nd December 2017","format":false,"excerpt":"Regulators have issued an advisory warning on 14th November to stop people taking Kratom after 36 deaths have been possibly associated with the drug. Already banned in several countries, the \"pick-me-up\" natural drug is created from picked Kratom leaves from jungles all over South East Asia. It was originally used\u2026","rel":"","context":"In "Medical"","block_context":{"text":"Medical","link":"https:\/\/www.groupactionlawyers.co.uk\/blog\/category\/medical"},"img":{"alt_text":"kratom legal high dangers","src":"https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/kratom-legal-high-min.png?fit=725%2C250&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/kratom-legal-high-min.png?fit=725%2C250&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/kratom-legal-high-min.png?fit=725%2C250&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/kratom-legal-high-min.png?fit=725%2C250&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":1498,"url":"https:\/\/www.groupactionlawyers.co.uk\/blog\/bodybuilding-products-bought-online-unsafe-experts-warn","url_meta":{"origin":1352,"position":5},"title":"Warnings over bodybuilding products bought online being unsafe and mislabelled","author":"Author","date":"2nd April 2018","format":false,"excerpt":"The internet has opened up the easiest way of accessing practically any kind of market, and many people - particularly young men - are turning to the internet in search of products they can use to help increase their muscle mass and improve their frame. But, experts are warning consumers\u2026","rel":"","context":"In "Health"","block_context":{"text":"Health","link":"https:\/\/www.groupactionlawyers.co.uk\/blog\/category\/health"},"img":{"alt_text":"warning claims over bodybuilding pills online","src":"https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/bodybuilding-pills-online-new.png?fit=1200%2C414&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/bodybuilding-pills-online-new.png?fit=1200%2C414&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/bodybuilding-pills-online-new.png?fit=1200%2C414&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/bodybuilding-pills-online-new.png?fit=1200%2C414&ssl=1&resize=700%2C400 2x, https:\/\/i0.wp.com\/www.groupactionlawyers.co.uk\/blog\/wp-content\/uploads\/bodybuilding-pills-online-new.png?fit=1200%2C414&ssl=1&resize=1050%2C600 3x"},"classes":[]}],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.groupactionlawyers.co.uk\/blog\/wp-json\/wp\/v2\/posts\/1352","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.groupactionlawyers.co.uk\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.groupactionlawyers.co.uk\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.groupactionlawyers.co.uk\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.groupactionlawyers.co.uk\/blog\/wp-json\/wp\/v2\/comments?post=1352"}],"version-history":[{"count":4,"href":"https:\/\/www.groupactionlawyers.co.uk\/blog\/wp-json\/wp\/v2\/posts\/1352\/revisions"}],"predecessor-version":[{"id":1357,"href":"https:\/\/www.groupactionlawyers.co.uk\/blog\/wp-json\/wp\/v2\/posts\/1352\/revisions\/1357"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.groupactionlawyers.co.uk\/blog\/wp-json\/wp\/v2\/media\/1359"}],"wp:attachment":[{"href":"https:\/\/www.groupactionlawyers.co.uk\/blog\/wp-json\/wp\/v2\/media?parent=1352"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.groupactionlawyers.co.uk\/blog\/wp-json\/wp\/v2\/categories?post=1352"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.groupactionlawyers.co.uk\/blog\/wp-json\/wp\/v2\/tags?post=1352"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}